Jean-Marc, a computer engineer, embarks on a train journey with no specific destination, seeking to escape the routine of his life. On the train, he meets Lonnie, an old man carrying a mysterious suitcase, who seems concerned by a sudden change in the train's route. When the compartment darkens into a tunnel, Jean-Marc discovers that Lonnie is suffering from a rare orphan disease and helps him recover from an acute respiratory attack.

 

Impressed by Jean-Marc's lively mind and ingenuity, Lonnie reveals to him that he is a retired inventor specializing in technologies medical. He invites Jean-Marc to join him in his field of research to collaborate on an innovative project. Together, they are developing a personalized diagnosis and treatment system for orphan diseases, combining biotechnology and skills IT by Jean-Marc.